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KMID : 0360319670020010029
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Journal of Korean Cancer Research Association
1967 Volume.2 No. 1 p.29 ~ p.39
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Tissue Growth Promoting Substance in Human Plasma
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Chin Byong-Ho
Chi Sam-Bong
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Abstract
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Effects of plasma promoting factor extracted from human plasma on growth of Ehrlich cancer in mice and on growth of Yoshida sarcoma in rats and also on mitosis of liver and kidnety of normal mice were studied.
Conclusions are as follows:
1) The human plasma factor promotes markedly growth of animal transplantable cancer, having shown also an incerase of the promotion s the injecting dosage being increased within the limit of a single dosage, while in over limit dosage the promotion seems to be decreased.
2) The human plasma factor promotes markedly the mitosis of normal tissues. On the other hand, promotion of cellular mitosis is sustained by continuous administration of plasma factor, but is most marked at a certain dosage. Further increase of injections results in decline of the rate of such promoting action gradually.
3) The mitotic action of the human plasma factor is more enhanced in liver tissue than in kidney.
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